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Case Report| Volume 14, ISSUE 4, e423-e425, August 2016

Gemcitabine and Paclitaxel for Primary Bladder Carcinoma in Renal Transplant Recipients: A Case Report

  • Zhi-Ke Li
    Affiliations
    Department of Medical Oncology, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan Province, People's Republic of China
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  • Ye Chen
    Affiliations
    Department of Medical Oncology, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan Province, People's Republic of China
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  • Yu Yang
    Affiliations
    Department of Medical Oncology, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan Province, People's Republic of China
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  • Ke Cheng
    Affiliations
    Department of Medical Oncology, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan Province, People's Republic of China
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  • Zhi-Ping Li
    Affiliations
    Department of Medical Oncology, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan Province, People's Republic of China
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  • Ji-Yan Liu
    Correspondence
    Address for correspondence: Ji-Yan Liu, PhD, MD, Department of Medical Oncology, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, No. 37, GuoXue Xiang, Chengdu 610041, Sichuan Province, People's Republic of China
    Affiliations
    Department of Medical Oncology, Cancer Center, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan Province, People's Republic of China
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Published:February 20, 2016DOI:https://doi.org/10.1016/j.clgc.2016.02.002
      In the present case, a patient with locally advanced primary bladder carcinoma (PBC) after renal transplantation was successfully treated with gemcitabine and paclitaxel combined with radiotherapy, and no severe adverse effects were observed.

      Keywords

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      References

        • Hevia V.
        • Gómez V.
        • Nicolás V.D.
        • et al.
        Development of urologic de novo malignancies after renal transplantation.
        Transplant Proc. 2014; 46: 170-175
        • Medani S.
        • O'Kelly P.
        • O'Brien K.M.
        • et al.
        Bladder cancer in renal allograft recipients: risk factors and outcomes.
        Transplant Proc. 2014; 46: 3466-3473
        • Prabharasuth D.
        • Moses K.A.
        • Bernstein M.
        • et al.
        Management of bladder cancer after renal transplantation.
        Urology. 2013; 81: 813-819
        • McCrea P.H.
        • Chang M.
        • Bailley G.
        • et al.
        Sarcomatoid carcinoma of the bladder after simultaneous kidney-pancreas transplant: a case report and review of the literature.
        BMJ Case Rep. 2012; 2012
        • Cheung C.Y.
        • Lam M.F.
        • Chu K.H.
        • et al.
        Malignancies after kidney transplantation: Hong Kong renal registry.
        Am J Transplant. 2012; 12: 3039-3046
        • Li X.B.
        • Xing N.Z.
        • Wang Y.
        • et al.
        Transitional cell carcinoma in renal transplant recipients: a single center experience.
        Int J Urol. 2008; 15: 53-57
        • Liu G.M.
        • Fang Q.
        • Ma H.S.
        • et al.
        Distinguishing characteristics of urothelial carcinoma in kidney transplant recipients between China and Western countries.
        Transplant Proc. 2013; 45: 2197-2202
        • Chiang Y.J.
        • Yang P.S.
        • Wang H.H.
        • et al.
        Urothelial cancer after renal transplantation: an update.
        Transplant Proc. 2012; 44: 744-745
        • Zhang A.
        • Shang D.H.
        • Zhang J.
        • et al.
        A retrospective review of patients with urothelial cancer in 3,370 recipients after renal transplantation: a single-center experience.
        World J Urol. 2015; 33: 713-717
        • Yu C.C.
        • Chen S.L.
        • Lian J.D.
        • et al.
        Primary ovary transitional cell carcinoma after renal transplantation.
        J Chin Med Assoc. 2011; 74: 230-232
        • Bellmunt J.
        • Maase H.V.D.
        • Mead G.M.
        • et al.
        Randomized phase III study comparing paclitaxel/cisplatin/gemcitabine and gemcitabine/cisplatin in patients with locally advanced or metastatic urothelial cancer without prior systemic therapy: EORTC Intergroup Study 30987.
        J Clin Oncol. 2012; 30: 1107-1113
        • Zhang P.
        • Zhang X.D.
        • Wang Y.
        • et al.
        Feasibility of pre- and postoperative gemcitabine-plus-cisplatin systemic chemotherapy for the treatment of locally advanced urothelial carcinoma in kidney transplant patients.
        Transplant Proc. 2013; 45: 3293-3297
        • Kojima Y.
        • Takahi Y.
        • Ichimaru N.
        • et al.
        Successful treatment of metastatic urothelial carcinoma arising in a transplanted renal allograft with paclitaxel, cisplatin, and gemcitabine combination therapy: a case report.
        BMC Res Notes. 2015; 8: 25
        • Benisovich V.I.
        • Silverman L.
        • Slifkin R.
        • et al.
        Cisplatin-based chemotherapy in renal transplant recipients: a case report and a review of the literature.
        Cancer. 1996; 77: 160-163
        • Matzkies F.K.
        • Tombach B.
        • Dietrich M.
        • et al.
        MVAC-therapy for advanced urothelial carcinoma in an anuric renal transplant recipient.
        Nephrol Dial Transplant. 2000; 15: 110-112