Abstract
Background
Methods
Results
Conclusions
Keywords
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Clinical Genitourinary CancerReferences
- World Cancer Report 2014.WHO, Geneva2014
- Complications of renal surgery.Urol Clin North Am. 2017; 44: 275-288
- Rising incidence of small renal masses: a need to reassess treatment effect.J Natl Cancer Inst. 2006; 98: 1331-1334
- Comparative effectiveness of surgical treatments for small renal masses.Urol Clin North Am. 2017; 44: 257-267
- Guidelines on renal cell carcinoma.Eur Assoc Urol. 2021; : 1-94
- Kidney cancer, version 2.2017, NCCN clinical practice guidelines in oncology.J Natl Compr Cancer Netw. 2017; 15: 804-834
- Renal mass and localized renal cancer: AUA guideline.J Urol. 2017; 198: 520-529
- Renal function after nephron-sparing surgery versus radical nephrectomy: results from EORTC randomized trial 30904.Eur Urol. 2014; 65: 372-377
- Comparison of perioperative outcomes between robotic and laparoscopic partial nephrectomy: a systematic review and meta-analysis.Eur Urol. 2015; 67 (Elsevier B.V.Accessed: Jan 29, 2021Available at:): 891-901
- Positive surgical margins in nephron-sparing surgery: risk factors and therapeutic consequences.World J Surg Oncol. 2014; 12 (BioMed Central Ltd.Accessed: Jan 29, 2021Available at:): 252-257
- Local tumor bed recurrence following partial nephrectomy in patients with small renal masses.J Urol. 2018; 199 (Accessed: Jan 29, 2021Available at:): 393-400
- Positive surgical margin appears to have negligible impact on survival of renal cell carcinomas treated by nephron-sparing surgery.Eur Urol. 2010; 57 (Accessed: Jan 29, 2021Available at:): 466-473
- Oncological outcomes and prognostic factors after nephron-sparing surgery in renal cell carcinoma.Int Urol Nephrol. 2016; 48 (Accessed: Jan 29, 2021Available at:): 681-686
- Positive surgical margins increase risk of recurrence after partial nephrectomy for high risk renal tumors.J Urol. 2016; 196 (Accessed: Jan 29, 2021Available at:): 327-334
- Positive surgical margins predict progression-free survival after nephron-sparing surgery for renal cell carcinoma: results from a single center cohort of 459 cases with a minimum follow-up of 5 years.Clin Genitourin Cancer. 2019; 17 (Accessed: Jan 29, 2021Available at:): e26-e31
- Cochrane handbook for systematic reviews of interventions version 5.1.0.Cochrane. 2011; : 1-639
- The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration.Ann Intern Med. 2009; 151: W65-W94
Garcia-Perdomo H, Vilaseca Cabo A. Effect of positive margins in patients who undergo a partial nephrectomy regarding recurrence, overall survival, recurrence/progression-free survival, and metastasis-free survival. A systematic review and meta-analysis. 2021. doi:10.6084/m9.figshare.14069000.v1
Schünemann H, Brożek J, Guyatt G, Oxman A, Editors. GRADE handbook for grading quality of evidence and strength of recommendations. The GRADE working group [Internet]. 2013. Available at: guidelinedevelopment.org/handbook, Aug 2, 2021.
- Zero ischemia off-clamp robotic partial nephrectomy: outcomes of a multicenter study.Eur Urol Suppl. 2016; 15: 238
- Localized chromophobe carcinomas treated by nephron-sparing surgery have excellent oncologic outcomes.Urol Oncol Semin Orig Investig. 2017; 35 (35.e15-35.e19)
- Effect of positive surgical margin on survival after partial nephrectomy for renal cell cancer: long-term results of a single center.J Urol Surg. 2020; 7: 316-324
- Predictive factors for recurrence after partial nephrectomy for clinical T1 renal cell carcinoma: a retrospective study of 1227 cases from a single institution.Int J Clin Oncol. 2020; 25: 892-898https://doi.org/10.1007/s10147-020-01632-x
- Vessel and tension-free reconstruction during robot-assisted partial nephrectomy for hilar tumors: “garland” technique and midterm outcomes.J Endourol. 2020; 34: 469-474
- Long-term oncologic outcomes of positive surgical margins following robot-assisted partial nephrectomy.Transl Androl Urol. 2020; 9: 879-886
- Pd46-03 negative impact of positive margins in partial nephrectomy in stage 1 renal cell carcinoma: a multicenter analysis.J Urol. 2019; 201: 54-56
- Assessment of clinicopathological predictors of local recurrence on tumor resection bed in patients treated with partial nephrectomy for localized renal cell carcinoma (the RECORd 1 project).Eur Urol Suppl. 2019; 18: e427-e428https://doi.org/10.1016/S1569-9056(19)30323-9
- Positive surgical margins during partial nephrectomy for renal cell carcinoma: results from Canadian kidney cancer information system (CKCis) collaborative.Can Urol Assoc J. 2017; 11: 182-187
- Impact of positive surgical margins after kidney nephron sparing surgery on clinical disease progression - a single centre experience at long-term follow-up.Eur Urol Suppl. 2017; 16: e2165https://doi.org/10.1016/S1569-9056(17)31324-6
- Predictors of local recurrence after partial nephrectomy: results from two-years follow up of a prospective multicentre study (RECORd 1 project).Eur Urol Suppl. 2017; 16: e1370-e1371https://doi.org/10.1016/S1569-9056(17)30844-8
- Surgical margin does not influence recurrence rate in pT1 clear cell renal cell carcinoma after partial nephrectomy: a multicenter study.J Surg Oncol. 2016; 114: 70-74
- Five-year oncologic outcomes after transperitoneal robotic partial nephrectomy for renal cell carcinoma.Eur Urol. 2016; 69: 1149-1154https://doi.org/10.1016/j.eururo.2015.12.004
- Reexamining the association between positive surgical margins and survival after partial nephrectomy in a large American cohort.J Endourol. 2016; 30: 698-703
- Robot-assisted laparoscopic nephron sparing surgery for tumors over 4 cm: operative results and preliminary oncologic outcomes from a multicentre French study.Eur J Surg Oncol. 2013; 39: 799-803
- Prospective multi-center study of oncologic outcomes of robot-assisted partial nephrectomy for pT1 renal cell carcinoma.BMC Urol. 2012; 12: 1
- Surgical and oncologic outcomes of laparoscopic partial nephrectomy: a Japanese multi-institutional study of 1375 patients.J Endourol. 2012; 26: 652-659
- Robot-assisted partial nephrectomy: 5-yr oncological outcomes at a single european tertiary cancer center.Eur Urol Focus. 2019; 5: 636-641https://doi.org/10.1016/j.euf.2017.10.005
- Oncologic outcomes in patients treated with endoscopic robot assisted simple enucleation (ERASE) for renal cell carcinoma: results from a tertiary referral center.Eur J Surg Oncol. 2019; 45: 1977-1982https://doi.org/10.1016/j.ejso.2019.03.045
- Low rate of cancer events after partial nephrectomy for renal cell carcinoma: clinicopathologic analysis of 1994 cases with emphasis on definition of “recurrence.”.Clin Genitourin Cancer. 2019; 17 (e1.): 209-215https://doi.org/10.1016/j.clgc.2019.03.004
- The effect of surgical margin on cancer-specific survival in patients treated with nephron-sparing surgery.Niger J Clin Pract. 2019; 22: 1070-1077
- Oncologic outcomes of patients with positive surgical margin after partial nephrectomy: a 25-year single institution experience.World J Urol. 2018; 36: 1093-1101https://doi.org/10.1007/s00345-018-2241-7
- Positive surgical margins are predictors of local recurrence in conservative kidney surgery for pT1 tumors.Int Braz J Urol. 2018; 44: 475-482
- Patterns and predictors of recurrence after partial nephrectomy for kidney tumors.J Urol. 2017; 197: 1403-1409https://doi.org/10.1016/j.juro.2016.12.046
- Functional and oncologic outcomes after nephron-sparing surgery in a solitary kidney: 10 years of experience.Int Braz J Urol. 2016; 42: 253-261
- Nephron-sparing surgery for renal tumors measuring more than 7 cm: morbidity, and functional and oncological outcomes.Clin Genitourin Cancer. 2014; 12: 19-27
- Laparoscopic partial nephrectomy: an experience in 227 cases.Actas Urol Esp. 2014; 38: 109-114
- Robotic laparoendoscopic single-site transumbilical partial nephrectomy: Functional and oncologic outcomes at 2 years.Urology. 2013; 82: 595-599https://doi.org/10.1016/j.urology.2013.05.010
- Is there a benefit to frozen section analysis at the time of partial nephrectomy?.Can J Urol. 2013; 20: 6778-6784
- Positive surgical margins in robot-assisted partial nephrectomy: a multi-institutional analysis of oncologic outcomes (Leave no tumor behind).J Urol. 2013; 190: 1674-1679https://doi.org/10.1016/j.juro.2013.05.110
- Prevalence and impact on survival of positive surgical margins in partial nephrectomy for renal cell carcinoma: a population-based study.BJU Int. 2013; 111: 1-6
- Predictive factors for ipsilateral recurrence after nephron sparing surgery in renal cell carcinoma.Jean-Christophe Bernhard. Eur Urol. 2010; 57: 2-17
- Prognostic factors influencing long-term survival of patients undergoing nephron-sparing surgery for nonmetastatic renal-cell carcinoma (RCC) with imperative indications.Ann Surg Oncol. 2010; 17: 544-551
- Impact of positive surgical margins in patients undergoing partial nephrectomy for renal cortical tumours.BJU Int. 2007; 99: 286-289
- Does the size of the surgical margin in partial nephrectomy for renal cell cancer really matter?.J Urol. 2002; 167: 61-64
- Partial nephrectomy for renal tumors: Lack of correlation between margin status and local recurrence.Am J Clin Pathol. 2015; 143: 645-651
- Predictors and oncological outcomes following positive surgical margins at partial nephrectomy.JUrol. 2008; 179: 2158
- Impact of positive surgical margins after partial nephrectomy.Eur Urol Open Sci. 2020; 21: 41-46
- Risk factors and prognostic implications for pathologic upstaging to T3a after partial nephrectomy.Minerva Urol e Nefrol. 2019; 71: 395-405
- Effect of positive surgical margin on survival after partial nephrectomy for renal cell cancer: long-term results of a single center.J Urol Surg. 2020; 7: 316-324
- Positive margin during partial nephrectomy: does cancer remain in the renal remnant?.Urology. 2011; 77 (Accessed: May 26, 2021Available at:): 1400-1403
- Positive surgical margins with renal cell carcinoma have a limited influence on long-term oncological outcomes of nephron sparing surgery.Urology. 2010; 75 (Accessed: May 26, 2021Available at:): 277-280
- Positive surgical margins after nephron-sparing surgery.Eur Urol. 2012; 61 (Accessed: May 26, 2021Available at:): 757-763
- The past, present and future of minimally invasive therapy in urology: a review and speculative outlook.Minim Invasive Ther Allied Technol. 2013; 22 (Taylor & FrancisAccessed: May 26, 2021Available at:): 200-209
- American Urological Association (AUA) Renal Mass and Localized Renal Cancer.American Urological Association, USA2017
Motzer R, Jonasch E, Agarwal N, Alva A, Beckermann K, Boyle S. NCCN clinical practice guidelines in oncology: kidney cancer. 2021.
- French committee of urologic oncology. Percutaneous ablation versus surgical resection for local recurrence following partial nephrectomy for renal cell cancer: a propensity score analysis (REPART study—UroCCR 71).Eur Urol Focus. 2021; 8: 210-216
- Risk group assessment and clinical outcome algorithm to predict the natural history of patients with surgically resected renal cell carcinoma.J Clin Oncol. 2002; 20 (Accessed: Mar 2, 2021Available at:): 4559-4566
- Improved prognostication of renal cell carcinoma using an integrated staging system.J Clin Oncol. 2001; 19 (Accessed: Mar 2, 2021Available at:): 1649-1657
- Systematic review of renal carcinoma prognostic factors.Actas Urol Esp. 2017; 41: 215-225https://doi.org/10.1016/j.acuroe.2017.03.010
- Predicting disease progression after nephrectomy for localized renal cell carcinoma: the utility of prognostic models and molecular biomarkers.Cancer. 2008; 113: 450-460